New Data From Immutep’s efti to be Presented at ESMO

Wednesday, 26. August 2020 14:00

SYDNEY, Australia, Aug. 26, 2020 (GLOBE NEWSWIRE) -- Immutep Limited (ASX: IMM; NASDAQ: IMMP) ("Immutep” or “the Company”), a biotechnology company developing novel immunotherapy treatments for cancer and autoimmune diseases, is pleased to announce new data is scheduled to be presented in four poster presentations at the ESMO Virtual Congress 2020 which is being held from 19 to 21 September 2020, Central European Summer Time (CEST).

The new data will be presented from Immutep’s phase II TACTI-002 and the investigator-initiated phase I clinical trial, INSIGHT which includes INSIGHT-004. All four poster presentations relate to the Company’s lead product candidate, eftilagimod alpha (“efti” or “IMP321”). Immutep will announce the data to the market and make the posters available on its website. 

ESMO is Europe's most prestigious oncology congress, attracting more than 29,000 industry participants from 137 countries last year. This year it is being held in a virtual format due to COVID-19.

Poster presentations:
   
Title: Initial results from a Phase II study (TACTI-002) of eftilagimod alpha (soluble LAG-3 protein) and pembrolizumab as 2nd line treatment for PD-L1 unselected metastatic head and neck cancer patients
Date: 17 September 2020, CEST
Presenter: Dr Martin Forster, University College London Hospital, London, United Kingdom
   
Title: Initial results from a Phase II study (TACTI-002) of eftilagimod alpha (soluble LAG-3 protein) and pembrolizumab in patients with PD-L1 unselected 1st line metastatic non-small cell lung carcinoma
Date: 17 September 2020, CEST
Presenter: Dr Margarita Majem, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
   
Title: Safety data from stratum D of the phase I INSIGHT platform trial evaluating feasibility of IMP321 (LAG-3Ig protein, eftilagimod alpha) combined with avelumab in advanced stage solid tumor entities
Date: 17 September 2020 CEST
Presenter:  Dr Thorsten O. Goetze, Krankenhaus Nordwest, University Cancer Center, Frankfurt am Main, Germany
   
Title: The phase I INSIGHT platform trial: Strata A and B evaluating feasibility of intratumoral and intraperitoneal IMP321 (soluble LAG-3 protein, eftilagimod alpha) in advanced solid tumors
Date: 17 September 2020 CEST
Presenter:  Prof Salah-Eddin Al-Batran, Institute of Clinical Cancer Research, Krankenhaus Nordwest GmbH in Frankfurt, Germany (IKF)

About TACTI-002

TACTI-002 is being conducted in collaboration with Merck & Co., Inc., Kenilworth, NJ, USA (known as “MSD” outside the United States and Canada). It is evaluating the combination of efti with MSD’s KEYTRUDA® (or pembrolizumab, an anti-PD-1 therapy) in up to 109 patients.

About INSIGHT and INSIGHT-004

INSIGHT is a phase I investigator-initiated study being conducted by Institute of Clinical Cancer Research, Krankenhaus Nordwest GmbH in Frankfurt, Germany (IKF). It is evaluating efti as a monotherapy in 12 patients with advanced solid malignancies.

INSIGHT-004 is the fourth arm (stratum D) of the INSIGHT trial and is being conducted under Immutep’s collaboration with Merck KGaA, Darmstadt, Germany, and Pfizer Inc. It is evaluating the safety, tolerability and recommended Phase II dose of efti when given in combination with avelumab in 12 patients with advanced solid malignancies.

Further information can be found on the Company’s website www.immutep.com or by contacting:

Australian Investors/Media:
Catherine Strong, Citadel-MAGNUS
+61 (0)406 759 268; cstrong@citadelmagnus.com

U.S. Media:
Tim McCarthy, LifeSci Advisors
+1 (212) 915.2564; tim@lifesciadvisors.com

 

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