Evotec and APEIRON Biologics start next project on the Cbl-b target

Thursday, 20. October 2011 07:27
Evotec AG /
Evotec and APEIRON Biologics start next project on the Cbl-b target
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Hamburg, Germany -20 October 2011: Evotec AG (Frankfurt Stock Exchange: EVT,
TecDAX) and Apeiron Biologics AG today announced that they have entered into a
further discovery project on the Cbl-b target, an excellent target for anti-
tumor immune therapy.

Cbl-b plays a role in both the adaptive and the innate immune system and its
manipulation therefore can effectively enhance anti-tumor activities both for
tumor antigen-specific cells and for those recognizing general features of tumor

Evotec will apply their skills and proprietary technologies in cellular assay
development and ultra-high throughput screening (uHTS) to identify biologically
active molecules from its corporate library that interact with Cbl-b. The aim of
the collaboration will be to take compounds identified by Evotec as being active
against this target or other relevant targets and further jointly optimize them
as basis for formal preclinical and clinical development.

Dr Werner Lanthaler, Chief Executive Officer of Evotec, commented: "We are very
pleased to start a new project with Apeiron. It is strategically important to be
involved in high promising early stage biotech projects."

Dr Hans Loibner, Chief Executive Officer at Apeiron Biologics, commented:
"Apeiron's substantial expertise in applied immunology and cancer immunotherapy
plus Evotec's remarkable skills in high-throughput methodology are an excellent
basis for the successful identification and development of novel drugs that
enhance the power of the immune system to combat cancer. This growing area has
major clinical and commercial potential. "

No financial details are disclosed.

Contact Evotec AG:
Dr Werner Lanthaler, Chief Executive Officer, Phone: +49.(0)40.56081-242,

Forward-Looking Statements - Information set forth in this press release
contains forward-looking statements, which involve a number of risks and
uncertainties. The forward-looking statements contained herein represent the
judgement of Evotec as of the date of this report. Such forward-looking
statements are neither promises nor guarantees, but are subject to a variety of
risks and uncertainties, many of which are beyond our control, and which could
cause actual results to differ materially from those contemplated in these
forward-looking statements. We expressly disclaim any obligation or undertaking
to release publicly any updates or revisions to any such statements to reflect
any change in our expectations or any change in events, conditions or
circumstances on which any such statement is based.

--- End of Message ---

Evotec AG
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